The PicoQuant Single Molecule workshop is organized back-to-back with MAF 2017.
Organized in Berlin from September 13th to 15th, 2017, the workshop aims to provide an interdisciplinary platform for the exchange of experience and information as well as sharing recent findings in the field of ultrasensitive optical detection down to the single molecule level and beyond the classical diffraction limit. The target audience are researchers and developers from Physics, Chemistry, Biology as well as from Life or Materials Science.
Ultrasensitive microscopy and spectroscopy techniques have become standard tools for fundamental biological and biomedical research, allowing studying the function and structure of individual biomolecules as well as interactions between them. The range of techniques and methods has steadily grown since the first report of single molecule detection in 1976.
Today, single molecules can be detected using either wide field or confocal fluorescence microscopy, Scanning Nearfield Optical Microscopy (SNOM), Atomic Force Microscopy (AFM), or Raman scattering. Time-resolved methods such as Fluorescence Lifetime Imaging (FLIM), Fluorescence Correlation Spectroscopy (FCS) or even multidimensional fluorescence methods are used on a daily basis in imaging facilities. Measurements beyond Abbe's diffraction limit are possible thanks to techniques such as Stimulated Emission Depletion Microscopy (STED), localization microscopy (PALM, STORM, dSTORM, GSDIM), or fluctuation microscopy (SOFI). Interest in super-resolution microscopy techniques has increased in recent years and their importance was recognized by awarding the Nobel Price in Chemisty 2014 to Eric Betzig, Stefan W. Hell, and W.E. Moerner.
The current focus in ultrasensitive optical detection lies not only on improving and extending the range of single molecule and super-resolution techniques, but also to use them for challenging applications ranging from chemical analysis to biophysics, biological and biomedical research, medical diagnostics, and materials research.
Find our more about this workshop on the PicoQuant website!